Plasma Thrombin TimePlasma thrombin time, or thrombin clotting time, measures how quickly a clot forms when a standard amount of bovine thrombin is added to a platelet poor plasma sample from the patient and to a normal plasma control sample After thrombin is added, the clotting time for each sample is compared and recorded. This test allows a quick but imprecise estimation of plasma fibrin ogen levels. Purpose
Patient preparation
Procedure and posttest care
Precautions
Reference valuesNormal thrombin times range from 7 to 12 seconds. Test results are usually reported with a normal control value. Abnormal findingsA prolonged thrombin time may indicate heparin therapy, hepatic disease, DIC, hypofibrinogenemia, or dysfibrinogenemia. Patients with prolonged thrombin times may require measurement of fibrinogen levels; in suspected DIC, the test for fibrin split products is also necessary. Interfering factors
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