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Home :: Activated clotting time Activated Clotting TimeActivated clotting time, or automated coagulation time (ACT), measures whole blood clotting time. This test is commonly performed during procedures that require extra corporeal circulation, such as cardiopulmonary by pass, ultra filtration, hemodialysis, and extra corporeal membrane oxygenation (ECMO). Purpose
Patient preparation
Procedure and posttest care
Precautions
Reference valuesIn a non-anticoagulated patient, normal activated clotting time is 107 seconds plus or minus 13 seconds. During cardiopulmonary bypass, heparin is titrated to maintain an activated clotting time between 400 and 600 seconds. During ECMO, heparin is titrated to maintain the activated clotting time between 220 and 260 seconds. Interfering factors
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